Can I put a tune-o-matic bridge on my guitar?

This is not a mod to be taken lightly. The main problem is that the tune-o-matic bridge has a 12″ radius that does not match the 7 1/4″ radius of the Jagstang, Mustang, Jaguar and Jazzmaster necks.

Joey wrote up a great article on the pros and cons of this mod and how to do it.
The Tune-O-Matic Bridge Mod