oh, boy...
well, first off, let's check the list, shall we?
1. Is the amp turned on? Is it a tube amp? Are the tubes working?
2. Is the volume on the amp turned up?
3. Is your lead cable broken? (open the ends to see)
4. Are you using any pedals? If so, make sure they are powered and connected properly.
5. Is the tab on the inside of the input jack bent? (open the control cavity, pull the plate up, insert your lead cable and make sure it's making proper contact.)
Start there.