Should sound good. Its not high output so it goes with the tradition of neck buckers being that way. The balance between pups will be way out though, neck pups are usually louder as it is.
If you fit the bucker straight in the bridge wont you get away with enlarging the current angled pickguard hole straight? You could dremmel it.
The problem with Strats is the strings are close to the body, so usually humbuckers are a pain to fit unless you raise the saddles high and shim the neck to compensate for your action.