For me, it would truly all depend upon application, but if I had to choose one amplifier to do the job for Stage, Studio, and Practice, then it would be the Alchemist.
Now, if it went down to individual needs
Practice = Cube
Home Recording = Cube
Live Performance = Alchemist
Band Rehearsal = Alchemist
Play Devoid of Pedals = Cube
Play a Blues Jam = Alchemist....and I'm sure you get a point now....
Oh, and is that the child of Cyrano up there?