Yes, but I don't think you understand what Lou and myself are saying.
Let's use Kurt as an example because everyone has a boner for him. Say he's playing through my setup, with my settings. Since my settings are overly "extreme" he will still sound like Kurt. By this I mean bass is not maxed and trebs and mids at min, or vice versa, you get it. It has to do with how your attack on the strings is, how stiff/loose you hold your pick, fretting, everything.
I could play through your setup I'm sure and have more or less the exact same sound I get through my own. It's a sweet little thing called physics man. I major in the topic so I know a thing or two about how this exactly works.